Text should be typed double-spaced, using 12-point font size, with 1â€ margins (top,
2. The text should be 2-5 pages in length (not including the title page).
All pages, except the title page must be numbered at the bottom, center.
Present background information on the protein of interest. Why is this protein of
Show the protein sequence alignment of a minimum of three proteins.
Create boxes around areas that show the highest degree of identity.
Mark those sequences that constitute potential post-translational modification
Name the type of post-translational modification predicted to occur
(phosphorylation, methylation etc.)
Mark those sequences that could be functional motifs or domains (nuclear
localization sequence, leucine zipper).
Answer the following questions. What is the dominant biochemical activity or
molecular interaction that your protein is predicted to carry out. Which sites on the
protein contribute to the process directly? Which sites contribute indirectly? How
does the biochemical activity or the molecular interactions relate to its biological
and physiological function? What is expected to occur to the organism if the gene
that generates the protein is inactivated?
Author, year, title, source, volume and page numbers.
Use the journal Biochemistry (American Chemical Society) format for references and